Soy isoflavone: The multipurpose phytochemical (Review)
نویسندگان
چکیده
منابع مشابه
Soy and Isoflavone Estrogenic Activity
349 The potential health benefits of soy, and the soy isoflavones in particular, are widely publicized. Although soy and soy isoflavones exhibit both risks and benefits (1,2), in this article we focus on the thyroid toxicity of genistein. Genistein is the major isoflavone synthesized by the soybean; genistein possesses both estrogenic and goitrogenic activities. The claimed benefits of genistei...
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Metabolic syndrome has a high prevalence (about 22.4% in adult individuals) in developed countries. Inflammation due to obesity and fat accumulation is the most important factor in the progression of metabolic syndrome. In cells which have a receptor for insulin hormone, inflammatory mediators target the insulin signaling pathway and cause insulin resistance. Peroxisome proliferator-activated r...
متن کاملAging of hippocampal neurogenesis and soy isoflavone
Throughout life, production of new neurons (granule cells) continues in the hippocampus of mammals including humans. Adult-generated granule cells play an important role in regulation of hippocampus-dependent cognitive functions and emotional behavior [1]. Each process of adult hippocampal neurogenesis is controlled by a variety of extrinsic and intrinsic factors. For instance, physical restrai...
متن کاملEstrogenic activity of glycitein, a soy isoflavone.
Glycitein (4',7-dihydroxy-6-methoxyisoflavone) accounts for 5-10% of the total isoflavones in soy food products. The biological activity of this compound has not been reported to date, although numerous studies have been performed with the other soy isoflavones, daidzein and genistein. Glycitein was isolated from soy germ to 99% purity. Weaning female B6D2F1 mice were dosed with glycitein (3 mg...
متن کاملThe soy isoflavone genistein decreases adipose deposition in mice.
Adipose tissue is responsive to estrogen and expresses both estrogen receptor alpha and beta. To test the hypothesis that the estrogenic soy isoflavone genistein can have effects on adipose tissue, juvenile or adult C57/BL6 mice were ovariectomized and given daily injections of vehicle, 17beta-estradiol (5 microg/kg.d) or genistein (8-200 mg/kg.d) sc for 21-28 d. To test effects of dietary geni...
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ژورنال
عنوان ژورنال: Biomedical Reports
سال: 2013
ISSN: 2049-9434,2049-9442
DOI: 10.3892/br.2013.129